Houston’s sprawling Texas Medical Center owes its beginnings to a foundation established by Monroe Dunaway Anderson, a founder of the international cotton firm Anderson, Clayton & Co. The foundation’s executives helped conceive what grew into the center, and Anderson left most of his substantial estate for this purpose. The Medical Center is home to over 40 medical institutions. Among them is the M.D. Anderson Cancer Center, one of the nation’s premier cancer facilities committed to the elimination of cancer in Texas, the nation, and the world through comprehensive research, prevention and treatment.